Metagenomic next-generation sequencing in sepsis
Sepsis
Sepsis or blood poisoning is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.
mNGS :
Metagenomic next-generation sequencing (mNGS) can be used to provide information on the diversity of biologically important resources, analyze DNA sequences, uncover details of metabolic pathways, identify homology-based genes, discover industrially important enzymes, and solve important problems such as the detection of viral and fungal pathogens, among others... Read more
Metagenomic next-generation sequencing in sepsis :
mNGS has the advantages of a short detection period and a high positive rate in the diagnosis of pathogens causing sepsis. Routine blood culture combined with mNGS can significantly reduce the mortality of septic patients. Early detection using mNGS can shorten the total hospitalization time and the ICU hospitalization time of patients with sepsis.
You can find more details in this topic here : https://pubmed.ncbi.nlm.nih.gov/36844396/
Unison Ultralow DNA NGS Library Preparation Kit